深圳欣博盛生物科技有限公司 a1

CD22 antibody [C2C3], C-term
货号:GTX114015 规格:100μl 目录价:¥4000
货号:GTX114015-S 规格:25μl 目录价:¥1700
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD22 antibody [C2C3], C-term
别名:
CD22 molecule , SIGLEC-2 , SIGLEC2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the Extracellular domain of human CD22. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.79 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
95
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
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