CD3 antibody [17A2] (APC)-单抗-深圳欣博盛生物科技有限公司

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CD3 antibody [17A2] (APC)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX01458-07

规格：100μg

目录价：￥2100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD3 antibody [17A2] (APC)

别名:

CD3 antigen, delta polypeptide , CD3 antigen, epsilon polypeptide , CD3 antigen, gamma polypeptide , CD247 antigen , T3d , AI504783 , CD3 , CD3epsilon , T3e , Ctg-3 , Ctg3 , T3g , 4930549J05Rik , A430104F18Rik , AW552088 , Cd3 , Cd3-eta , Cd3-zeta , Cd3h , Cd3z , Cd3zeta , T3z , Tcrk , Tcrz

产品描述:

The 17A2 antibody reacts with the mouse CD3 complex, comprised of CD3 epsilon, CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The 17A2 antibody is a widely used phenotypic marker for mouse T cells. In addition, as the CD3e chain within the TCR complex contains intracellular signaling domains, binding of 17A2 antibody to CD3 can induce cell activation (use format suitable for functional assays).

反应种属:

Mouse

宿主来源:

Rat

实验应用:

FCM

同种型:

IgG2b

克隆性:

Monoclonal

克隆号:

17A2