| 货号:GTX01459 | 规格:100μg | 目录价:¥1500 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD3 antibody [Hit3a]
别名:
CD3d molecule , CD3e molecule , CD3g molecule , CD247 molecule , CD3-DELTA , IMD19 , T3D , IMD18 , T3E , TCRE , CD3-GAMMA , IMD17 , T3G , CD3-ZETA , CD3H , CD3Q , CD3Z , IMD25 , T3Z , TCRZ
产品描述:
The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3.
反应种属:
Chimpanzee, Human
宿主来源:
Mouse
实验应用:
Activation, FCM, ICC/IF, IHC-Fr, Neutralizing /Inhibition
同种型:
IgG2a
克隆性:
Monoclonal
克隆号:
Hit3a
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
生产商:
GeneTex
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