| 货号:GTX16669 | 规格:500μl | 目录价:¥7000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD3 antibody [SP7]
别名:
CD3d molecule , CD3-DELTA , IMD19 , T3D
反应种属:
Human, Mouse, Pig, Rat
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, IHC-Fr, IHC-P
靶标/特异性:
This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues.
同种型:
IgG
免疫原:
A synthetic 13-mer peptide corresponding to aa 156-168 of the ε chain of human CD3 protein.
克隆性:
Monoclonal
克隆号:
SP7
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
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