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折扣/货期| 货号：GTX01461-06 | 规格：100test | 目录价：￥1500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD4 antibody [SK3] (FITC)
别名:
CD4 molecule , CD4 , CD4mut
产品描述:
The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.
反应种属:
Cynomolgus monkey, Human, Rhesus Monkey
宿主来源:
Mouse
实验应用:
FCM
同种型:
IgG1
克隆性:
Monoclonal
克隆号:
SK3
纯化方式:
Purified by affinity chromatography
偶联:
FITC
产品浓度:
0.012 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
生产商:
GeneTex
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