CD40 antibody [LOB7/6] (PE)-单抗-深圳欣博盛生物科技有限公司

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CD40 antibody [LOB7/6] (PE)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX75205

规格：100test

目录价：￥7600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD40 antibody [LOB7/6] (PE)

别名:

CD40 molecule , Bp50 , CDW40 , TNFRSF5 , p50

反应种属:

Dog, Human

宿主来源:

Mouse

实验应用:

FCM

靶标/特异性:

This antibody recognizes the human CD40.

同种型:

IgG2a

免疫原:

CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG.

克隆性:

Monoclonal

克隆号:

LOB7/6

纯化方式:

Purified IgG

偶联:

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]

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