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折扣/货期| 货号：GTX01484-07 | 规格：100test | 目录价：￥5800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD40L / CD154 antibody [5C8] (APC)
别名:
CD40 ligand , CD154 , CD40L , CD40LG , HIGM1 , IGM , IMD3 , TBAM , TNFSF5 , TRAP , gp39 , hCD40L
产品描述:
The 5C8 antibody reacts with human CD154 which is also known as CD40L (CD40 ligand). CD154 is a 39kDa member of the TNF-α superfamily and is predominantly expressed on activated T cells but is also expressed on NK cells, mast cells, basophils, and eosinophils. CD154 binds to CD40, a molecule that is expressed on antigen presenting cells including B cells, monocytes/macrophages, and dendritic cells. The interaction of CD154 and CD40 regulates the activation of antigen presenting cells and is critical for B cell costimulation. The 5C8 antibody has been reported to block CD40L-CD40 interactions.
反应种属:
Cynomolgus monkey, Human, Rhesus Monkey
宿主来源:
Mouse
实验应用:
FCM
同种型:
IgG2a
克隆性:
Monoclonal
克隆号:
5C8
纯化方式:
Purified by affinity chromatography
偶联:
APC
产品浓度:
0.05 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
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