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折扣/货期| 货号：AG-40B-0107-3010 | 规格：3 x 10 ug | 目录价：￥7440 |
| 货号：AG-40B-0107-C010 | 规格：10 ug | 目录价：￥3720 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD40L (rat) (multimeric) (rec.) MultiPack
别名:
MultimericCD40L™; ACRP30headless:CD40L; ACRP30headless:CD154; ACRP30headless:TNFSF5; ADIPOQ-CD40L
产品描述:
MultimericCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to CD40L+enhancer combinations. MultimericCD40L™ has been shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM (Bone marrow-derived macrophages) viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators. The secretion of caspase-1 independent inflammatory mediators has been shown to be unaltered or even enhanced.
宿主来源:
CHO cells
靶标/特异性:
Binds to rat, human and mouse CD40.
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~35-40kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces B cell activation (as demonstrated by dose-dependent upregulation of CD86).
内毒素水平:
<0.02EU/µg purified protein (LAL test; Lonza).
促销活动
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