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折扣/货期| 货号：GTX02698 | 规格：100μg | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD45RB antibody [PTPRC/1783R]
别名:
protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200
反应种属:
Human
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
Recombinant full-length human CD45RB protein
克隆性:
Monoclonal
克隆号:
PTPRC/1783R
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
147
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
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