| 货号:GTX54447 | 规格:50μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD46 antibody [M177]
别名:
AHUS2,CD46,CD46 molecule,MCP,MIC10,TLX,TRA2.10
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, Functional Assay, IHC-Fr, IP, WB
靶标/特异性:
This antibody stains the extracellular domain of CD46. The monoclonal antibody M177 reacts with the SCR2 domain.
同种型:
IgG1
免疫原:
Purified MCP
克隆性:
Monoclonal
克隆号:
M177
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
100 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, 0.1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
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