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折扣/货期| 货号：GTX60658 | 规格：100μg | 目录价：￥5800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD59 antibody [8D2B8]
别名:
CD59 molecule (CD59 blood group) , 16.3A5 , 1F5 , EJ16 , EJ30 , EL32 , G344 , HRF-20 , HRF20 , MAC-IP , MACIF , MEM43 , MIC11 , MIN1 , MIN2 , MIN3 , MIRL , MSK21 , p18-20
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.
克隆性:
Monoclonal
克隆号:
8D2B8
纯化方式:
Protein G Purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
14
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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