| 货号:V4828SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Macrophage migration inhibitory factor Antibody / MIF
产品描述:
Macrophage migration inhibitory factor, also known as MIF or glycosylation inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor Alpha (TNF-Alpha), interleukin-1 (IL-1) and interferon-Gamma (IFN-Gamma). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P
同种型:
Mouse IgG
免疫原:
A recombinant fragment of human protein was used as the immunogen for the Macrophage migration inhibitory factor antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
MIF/6277
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Macrophage migration inhibitory factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
上一个:Macrophage migration inhibitory factor Antibody / MIF
下一个:MIF Antibody / GLIF / Glycosylation inhibiting factor
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