CD8 alpha antibody [53-6.7] (APC)-单抗-深圳欣博盛生物科技有限公司

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CD8 alpha antibody [53-6.7] (APC)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80266

规格：100μg

目录价：￥4200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD8 alpha antibody [53-6.7] (APC)

别名:

CD8 antigen, alpha chain , BB154331 , Ly-2 , Ly-35 , Ly-B , Lyt-2

产品描述:

The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

反应种属:

Mouse

宿主来源:

Rat

实验应用:

FCM

同种型:

IgG2a

免疫原:

Mouse spleen cells

克隆性:

Monoclonal