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折扣/货期| 货号：GTX75282 | 规格：200μg | 目录价：￥8700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD8 antibody [2ST8.5H7]
别名:
P37 Antibody , LYT3 Antibody , CD8B Antibody , LY3 Antibody , LEU2 Antibody , CD8b molecule Antibody , CD8B1 Antibody
反应种属:
Cynomolgus monkey, Human, Rhesus Monkey
宿主来源:
Mouse
实验应用:
FCM, IP, WB
靶标/特异性:
The antibody binds to the beta chain, recognising an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.
同种型:
IgG2a
免疫原:
Normal human T lymphocytes
克隆性:
Monoclonal
克隆号:
2ST8.5H7
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
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