| 货号:GTX20989 | 规格:50μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CDC25A antibody
别名:
CDC25A , CDC25A2 , cell division cycle 25A
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IP, WB
同种型:
IgG
免疫原:
Synthetic peptide representing a portion of the protein encoded by exon 7 (LocusLink ID 993).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
59
产品形式:
Liquid
存储溶液:
Tris-Citrate/Phosphate, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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