CDK4 antibody [DCS 31.2]-单抗-深圳欣博盛生物科技有限公司

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CDK4 antibody [DCS 31.2]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX75694

规格：100μg

目录价：￥10300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CDK4 antibody [DCS 31.2]

别名:

cyclin dependent kinase 4 , CMM3 , PSK-J3

反应种属:

Human, Mouse, Rat

宿主来源:

Mouse

实验应用:

IHC-Fr, IP, WB

靶标/特异性:

This antibody does not cross react with other cdk's and does not co-precipitate the D type cyclins bound to cdk4.

同种型:

IgG1

克隆性:

Monoclonal

克隆号:

DCS 31.2

纯化方式:

Purified IgG

偶联:

Unconjugated

产品浓度:

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.08% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]

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