| 货号:GTX15050 | 规格:50μg | 目录价:¥5000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
C/EBP beta antibody [1H7]
别名:
CCAAT/enhancer binding protein (C/EBP), beta , C/EBPbeta , CRP2 , IL-6DBP , LAP , LIP , NF-IL6 , NF-M , Nfil6
反应种属:
Mouse, Rat
宿主来源:
Mouse
实验应用:
ChIP assay, Gel supershift assays, ICC/IF, IP, WB
靶标/特异性:
This antibody detects the LAP*, LAP and LIP isoforms of C/EBP beta.
同种型:
IgG
免疫原:
Recombinant mouse LIP.
克隆性:
Monoclonal
克隆号:
1H7
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues.? These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP.? One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells.? Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation.? From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.
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