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折扣/货期| 货号：GTX22784 | 规格：100μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CFTR antibody [CF3]
别名:
cystic fibrosis transmembrane conductance regulator , ABC35 , ABCC7 , CF , CFTR/MRP , MRP7 , TNR-CFTR , dJ760C5.1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC, IHC-P, IP, Neutralizing/Inhibition, WB
靶标/特异性:
This antibody detects one or more immunologically related proteins in mouse cell line Heb7a that does not contain CFTR mRNA.
同种型:
IgM
免疫原:
Synthetic Peptide: G(103) R I I A S Y D P D N K E E R(117)
克隆性:
Monoclonal
克隆号:
CF3
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
168
产品形式:
Liquid
存储溶液:
Ascites, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]
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