官网链接
折扣/货期| 货号：GTX10987 | 规格：50μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CGRP antibody [4901]
别名:
calcitonin-related polypeptide alpha , CAL6 , CGRP , Cal1 , Calc , RATCAL6 , calcitonin
反应种属:
Dog, Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC, IHC-Fr, Neutralizing/Inhibition, RIA, WB
同种型:
IgG1
免疫原:
rat α-CGRP peptide. The epitope recognized by the antibody resides within the C-terminal ten amino acids of rat α-CGRP.
克隆性:
Monoclonal
克隆号:
4901
纯化方式:
Purified immunoglobulin
偶联:
Unconjugated
产品浓度:
2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Calcitonin gene-related peptide (CGRP), amylin (AMY), and adrenomedullin (ADM) are structurally related peptides of the same family. They are characterized by six to seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. CGRP is a 37 amino acid peptide derived from the alternative splicing, which is tissue specific, of the calcitonin gene and may exist in two forms alpha and beta with similar biological functions. Calcitonin gene-related peptide is widely found in both the central and peripheral (sensory and motor neurons) nervous systems. Structural activity studies have found that following peripheral or intracerebroventricular injections of CGRP, several biological actions have been demonstrated that are mediated by the activation of the CGRP receptor subtypes designated CGRP1 and CGRP2. BIBN4096BS, a potent non-peptide antagonist, competitively antagonizes the effects of CGRP in the rat atrium with a potency of about 10-fold higher than that of CGRP (8-37). BIBN4096BS was much less potent at antagonizing the effects of CGRP, proposed to be mediated by the CGRP2 subtype. An orphan receptor originally described as the calcitonin-receptor- like receptor (CRLR) has been identified as a CGRP receptor. Co-expression with a single transmembrane receptor, termed receptor-activity-modifying protein 1 (RAMP1), is required for this receptor to behave as a CGRP1 receptor.
您可能感兴趣的产品
Alpha Synuclein Oligomer Antibody
货号：SMC-622S
Alpha Synuclein Oligomer Antibody: RPE
货号：SMC-622D-RPE
Alpha Synuclein Oligomer Antibody: PerCP
货号：SMC-622D-PCP
Alpha Synuclein Oligomer Antibody: HRP
货号：SMC-622D-HRP
Alpha Synuclein Oligomer Antibody: FITC
货号：SMC-622D-FITC
Alpha Synuclein Oligomer Antibody: Biotin
货号：SMC-622D-BI
Alpha Synuclein Oligomer Antibody: APC
货号：SMC-622D-APC
Alpha Synuclein Oligomer Antibody: ATTO 594
货号：SMC-622D-A594
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询