| 货号:GTX25692 | 规格:100μg | 目录价:¥7200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CIDE A antibody
别名:
CIDEA , cell deathinducing DFFAlike effector a , CIDE A , cell death inducing DFFA like effector a
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, IHC-P, WB
靶标/特异性:
This antibody recognizes human CIDE-A (23kDA) and does not cross-react with CIDE-B.
同种型:
IgG
免疫原:
Peptide corresponding to aa 200-217 of human CIDE-A (accession no. AF041378)
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
25
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
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