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折扣/货期| 货号：AG-CR1-3626-M001 | 规格：1 mg | 目录价：￥420 |
| 货号：AG-CR1-3626-M005 | 规格：5 mg | 目录价：￥1200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CK2 Inhibitor 10
别名:
CK2-VIII; 4-(2-(4-Methoxybenzamido)thiazol-5-yl)benzoic acid
产品描述:
Potent and ATP-competitive inhibitor of casein kinase 2 (IC50 CK2alpha=32nM and IC50 CK2alpha'=46nM). Potently also inhibits DYRK1B and FLT3. Anticancer compound. Exhibits potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116 and breast cancer cells MCF-7. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
354.4 . 9.0
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC, MS, NMR)
CAS号:
1361229-76-6
分子式:
C18H14N2O4S . 0.5H2O
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