官网链接
折扣/货期| 货号：GTX78175 | 规格：100μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CLACP antibody
别名:
collagen type XXV alpha 1 chain , AMY , CFEOM5 , CLAC , CLAC-P , CLACP
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
Reacts with residues 430-443 [DYNGNLHEALQRIT] of the NC3 region of human and mouse CLAC-P.
同种型:
IgG
克隆性:
Polyclonal
克隆号:
纯化方式:
Affinity purified IgG
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
65
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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