CLP1 antibody [N3C3]-多抗-深圳欣博盛生物科技有限公司

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CLP1 antibody [N3C3]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX115518-S	规格：25μl	目录价：￥1700
货号：GTX115518	规格：100μl	目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CLP1 antibody [N3C3]

别名:

cleavage and polyadenylation factor I subunit 1 , HEAB , hClp1

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, IP, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human CLP1. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.27 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

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