COL18A1 antibody, N-term-多抗-深圳欣博盛生物科技有限公司

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COL18A1 antibody, N-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80984

规格：400μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

COL18A1 antibody, N-term

别名:

collagen type XVIII alpha 1 chain , KNO , KNO1 , KS

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

FCM, WB

同种型:

IgG

免疫原:

KLH conjugated synthetic peptide between 237-263 amino acids from the N-terminal region of human COL18A1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Protein A purified, followed by peptide affinity purification.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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