深圳欣博盛生物科技有限公司 a1

Complement Component C5a Recombinant Protein
品牌:ProSci LLC
货号:11-368 规格:0.1 mg 目录价:¥10126.35
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Complement Component C5a Recombinant Protein
别名:
C5a,Complement Component 5a
实验应用:
ELISA,WB
表达系统:
E. coli
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
PBS, pH7.4
产地:
美国
生产商:
Prosci
功能与背景:
Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells; C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation; C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism; C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system; C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
纯度:
>95% as determined by SDS-PAGE.
Accession #:
 NP_034536.2
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