Creatine kinase MT antibody [AT17A2]-单抗-深圳欣博盛生物科技有限公司

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Creatine kinase MT antibody [AT17A2]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX53700

规格：100μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Creatine kinase MT antibody [AT17A2]

别名:

creatine kinase, mitochondrial 1A , CKMT1 , U-MtCK , mia-CK

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, WB

同种型:

IgG2b

免疫原:

Recombinant human CKMT1A (40-417aa) purified from E. coli

克隆性:

Monoclonal

克隆号:

AT17A2

纯化方式:

By protein-A affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 10% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]

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