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折扣/货期| 货号：GTX27540 | 规格：100μl | 目录价：￥9200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CREB antibody
别名:
cAMP responsive element binding protein 1 , CREB , CREB-1
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ChIP assay, ELISA, EMSA, WB
靶标/特异性:
A partial cross-reactivity is observed against CREM-1 protein.
同种型:
IgG
免疫原:
CREB-1 (p43) peptide corresponding to a region near the N-terminus of the human protein, conjugated to KLH.
克隆性:
Polyclonal
克隆号:
偶联:
Unconjugated
产品浓度:
2.56 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
cyclic AMP responsive element binding protein (CREB) is a ubiquitous transcription factor regulated by changes in cyclic AMP (cAMP) levels. CREB binds as a homodimer to CRE sites (cAMP response elements) and belongs to the basic leucine zipper family of DNA binding proteins. Increases in cAMP levels result in the specific phosphorylation of CREB by protein kinase A. Phosphorylated CREB interacts with the transcriptional co-activator CBP (CREB binding protein or p265). It has recently been demonstrated that CREB phosphorylation correlates with light regulated circadian rhythms.
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