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折扣/货期| 货号：GTX79097 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CRK (phospho Tyr221) antibody
别名:
CRK,CRK protooncogene, adaptor protein,CRKII,p38,CRK II,CRK2,Crk p38,CRK proto-oncogene, adaptor protein
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
This antibody was raised against CRK2 protein, and it may not recognize CRK1 protein.
同种型:
IgG
免疫原:
The antiserum was produced against synthesized phosphopeptide derived from human Crk2 around the phosphorylation site of tyrosine 221 (G-P-Yp-A-Q).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
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