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折扣/货期| 货号：GTX52659 | 规格：50μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CTLA4 antibody [8F16]
别名:
ALPS5 , CD , CD152 , CELIAC3 , CTLA4 , GRD4 , GSE , IDDM12 , cytotoxic Tlymphocyte associated protein 4 , cytotoxic T-lymphocyte associated protein 4
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG2
免疫原:
Human recombinant CTLA-4
克隆性:
Monoclonal
克隆号:
8F16
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
500 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
25
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
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