| 货号:GTX27199 | 规格:50μg | 目录价:¥4300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CXCR4 antibody
别名:
C-X-C Motif Chemokine Receptor 4 , Cxcr4
反应种属:
Mouse, Rat
宿主来源:
Rabbit
实验应用:
FCM, IM, WB
同种型:
IgG
免疫原:
Recombinant full length protein (Rat).
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library (ref 1). Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor forHIV-2's binding to CD4 through envelope glycoprotein gp 120 (ref 2). In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells (ref 3). Mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.
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