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折扣/货期| 货号：GTX01660 | 规格：500μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cyclin D1 antibody [ZM178]
别名:
cyclin D1 , BCL1 , D11S287E , PRAD1 , U21B31
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, Neutralizing/Inhibition
同种型:
IgG2a
免疫原:
Synthetic peptide corresponding to residues within aa 200-295 of human Cyclin D1
克隆性:
Monoclonal
克隆号:
ZM178
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]
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