Cyclin E2 antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Cyclin E2 antibody

买大送小新年开门红～买大送小，好礼四选一！

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX48724

规格：50μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Cyclin E2 antibody

别名:

cyclin E2

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

ELISA, IP, WB

同种型:

IgG

免疫原:

Synthetic peptide corresponding to amino acids at the carboxyl terminus of the Cyclin E2 protein.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1.17 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

Cyclin E was first identified by its ability to rescue growth of yeast deficient in G1 Cyclins, indicating a role in G1 or G1/S transitions.Over-expression of Cyclin E has been observed in a variety of human tumors. Multiple isoforms of Cyclin E are expressed in tumors but not in normal tissues, suggesting a post-transcriptional regulation of Cyclin E. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27Kip1 and p21Cip1. The catalytic activity associated with Cyclin E2 complexes is cell cycle regulated and peaks at the G1/S transition. Unlike Cyclin E1, which is expressed in most proliferating normal and tumor cells, Cyclin E2 levels were low to undetectable in non-transformed cells and increased significantly in tumor-derived cells.

您可能感兴趣的产品

Strep-Tag Polyclonal Antibody

货号：ORF.STREPPAB-50

mCherry Polyclonal Antibody

货号：ORF.MCHERPAB-50

MBP Polyclonal Antibody