官网链接
折扣/货期| 货号：V4458-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V4458-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cytokeratin 14 Antibody / CK14 / KRT14
产品描述:
Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. It always pairs with the type II keratin K5 and form the primary keratin pair of the keratinocytes of stratified squamous epithelia, including the epidermis as well as mucosal non-keratinizing stratified squamous epithelia. Cytokeratin 14 is strongly expressed in the undifferentiated basal cell layer containing the stem cells and are down-regulated in the differentiating suprabasal cell layers. Otherwise, in the widely well stratified follicular outer root sheath, cytokeratin 14 is uniformly expressed throughout all layers. The expression spectrum of cytokeratin 14 in tumors corresponds well to the patterns in normal epithelia. Thus, most squamous cell carcinomas as well as malignant mesotheliomas strongly express this keratin whereas little, focal, or no expression is found in adenocarcinomas.Cytokeratin 14 may be a useful marker in the differential diagnosis of squamous cell carcinoma from other epithelial tumors. Recent studies also indicate that CK14 expression in breast cancer corresponded with poor clinical outcome and that CK14 may have diagnostic value in the sub-classification of NSCLC.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A recombinant human KRT14 fragment (within amino acids 350-472) was used as the immunogen for the Cytokeratin 14 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
KRT14/6987R
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Cytokeratin 14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
您可能感兴趣的产品
Dengue Virus Antibody [5161]
货号：XV-2049
NMDA NR1 Antibody [R1JHL]
货号：XPS-2019
Progesterone Receptor (phospho Ser294) Antibody [608]
货号：XPS-1024
Progesterone Receptor (phospho Ser190) Antibody [1154]
货号：XPS-1023
VEGF Antibody [4B2-8]
货号：XP-5740-M
IFN-gamma Antibody [1.1-5A9-2D05]
货号：XP-5739-M
RANTES Antibody [5B3-D5]
货号：XP-5735-M
MIP-1a Antibody [1.2_3E8-2H6-2B6]
货号：XP-5734-M
促销活动
复制QQ号成功，请打开QQ后添加好友进行咨询