| 货号:GTX12208 | 规格:100μg | 目录价:¥5000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
D type cyclin antibody
别名:
D type cyclin encoded by Kaposis Sarcoma Virus Vcyc
反应种属:
Kaposi's sarcoma-associated herpesvirus
宿主来源:
Rat
实验应用:
ICC/IF, IP, WB
同种型:
IgG
免疫原:
Recombinant fusion protein produced from a clone from KSV.
克隆性:
Monoclonal
克隆号:
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
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