DAP12 antibody-多抗-深圳欣博盛生物科技有限公司

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DAP12 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX16462

规格：100μg

目录价：￥7500

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DAP12 antibody

别名:

TYRO protein tyrosine kinase binding protein , DAP12 , KARAP , PLOSL , PLOSL1

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

IP, WB

同种型:

IgG

免疫原:

Recombinant full length protein (Human).

克隆性:

Polyclonal

克隆号:

纯化方式:

IgG fraction

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.08% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

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