| 货号:GTX105963-S | 规格:25μl | 目录价:¥1700 |
| 货号:GTX105963 | 规格:100μl | 目录价:¥4000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DCAMKL2 antibody [N2C2], Internal
别名:
doublecortin like kinase 2 , CL2 , CLICK-II , CLICK2 , CLIK2 , DCAMKL2 , DCDC3 , DCDC3B , DCK2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human DCAMKL2. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.16 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
84
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq]
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