深圳欣博盛生物科技有限公司 a1

MAPKBP1 Antibody
品牌:ProSci LLC
货号:18-741 规格:100 uL 目录价:¥7651.8
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MAPKBP1 Antibody
别名:
JNKBP-1, JNKBP1, NPHP2mitogen-activated protein kinase-binding protein 1, JNK-binding protein 1
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
WB,IHC
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
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