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折扣/货期| 货号：GTX66840 | 规格：100μl | 目录价：￥6500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DDX3 antibody [6G8]
别名:
DEAD-box helicase 3 X-linked , CAP-Rf , DBX , DDX14 , DDX3 , HLP2 , MRX102
反应种属:
Human, Monkey, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG
免疫原:
Purified recombinant human DDX3 protein fragments expressed in E.coli.
克隆性:
Monoclonal
克隆号:
6G8
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
73
产品形式:
Liquid
存储溶液:
100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
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