Deleted in breast cancer 2 Antibody / DBC2 / RHOBTB2-单抗-深圳欣博盛生物科技有限公司

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Deleted in breast cancer 2 Antibody / DBC2 / RHOBTB2

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5242-100UG	规格：100 ug	目录价：￥6652.1
货号：V5242-20UG	规格：20 ug	目录价：￥3082.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Deleted in breast cancer 2 Antibody / DBC2 / RHOBTB2

产品描述:

The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. DBC-2 (deleted in breast cancer 2 gene protein), also known as RHOBTB2 (Rho-related BTB domain-containing protein 2), is a 727 amino acid member of the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. Expressed ubiquitously with highest levels in neural tissue, heart, brain and fetal lung, DBC-2 contains two BTB (POZ) domains through which it may bind to and regulate the function of target proteins, such as CUL-3. Additionally, DBC-2 is thought to function as a regulator of cell cycle and apoptosis events. Under normal conditions, DBC-2 is thought to exhibit tumor suppressor activity. Mutations in the gene encoding DBC-2 are associated with breast cancer, suggesting that mutated DBC-2 may play a role in carcinogenesis.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2, kappa

免疫原:

A recombinant partial protein sequence (within amino acids 554-604) from the human protein was used as the immunogen for the Deleted in breast cancer 2 antibody.

克隆性:

Monoclonal (mouse origin)

克隆号:

DBC2/4570

纯化方式:

Protein A/G affinity

保存温度:

Aliquot the Deleted in breast cancer 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

产品形式:

Purified

存储溶液:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide