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折扣/货期| 货号：SIH-382-50MG | 规格：50 mg | 目录价：￥3729.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dimethyloxaloylglycine (DMOG)
别名:
DMOG, N-(Methoxyoxoacetyl)-glycine methyl ester
产品描述:
Prolyl-4-hydroxylase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
175.1
产品形式:
Off-white solid
产地:
加拿大
功能与背景:
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.
纯度:
>99%
来源:
Synthetic
CAS号:
89464-63-1
分子式:
C6H9NO5
溶解度:
Soluble in DMSO (>25 mg/ml), 100% ethanol (>25 mg/ml) or dimethyl formamide, or PBS pH7.2 (10 mg/ml)
PubChem CID:
560326
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