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折扣/货期| 货号：GTX13887 | 规格：100μg | 目录价：￥6700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DNMT3A antibody [64B814.1]
别名:
DNA methyltransferase 3A , MmuIIIA
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, WB
同种型:
IgG1
免疫原:
This antibody was raised against bacteria expressed HIS-tag recombinant mouse Dnmt3a.
克隆性:
Monoclonal
克隆号:
64B814.1
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
102
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity.
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