DNMT3L antibody-多抗-深圳欣博盛生物科技有限公司

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DNMT3L antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX66194

规格：100μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DNMT3L antibody

别名:

DNA methyltransferase 3 like

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

Recombinant funsion protein containing a sequence corresponding to amino acids 151-386 of human DNMT3L (NP_787063.1).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

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