DUSP3 antibody [N1C3]-多抗-深圳欣博盛生物科技有限公司

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DUSP3 antibody [N1C3]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX109149	规格：100μl	目录价：￥4000
货号：GTX109149-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DUSP3 antibody [N1C3]

别名:

dual specificity phosphatase 3 , VHR

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

IgG

免疫原:

Full length human DUSP3 Recombinant protein.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.58 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq]

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