| 货号:GTX84594 | 规格:10μg | 目录价:¥7300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DYNC1LI1 antibody [2E8]
别名:
lin-28 homolog B , CSDD2
克隆号:
偶联:
Unconjugated
产品浓度:
0.25 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 200mM NaCl, 10% Glycerol, 2mM DTT, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
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