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折扣/货期| 货号：GTX26305 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dynein Heavy chain antibody [440.4]
别名:
dynein axonemal heavy chain 9
反应种属:
Chicken, Human
宿主来源:
Mouse
实验应用:
Dot, ELISA, ICC/IF, WB
同种型:
IgG2a
免疫原:
cytoplasmic dynein from chicken embryo brain.
克隆性:
Monoclonal
克隆号:
440.4
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Eukaryotic cells rely on actin and microtubule-based protein ""motors"" to generate intracellular movements (3). These protein ""motors"" contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kD), three intermediate chains (70-125 kD), and at least four light chains (15-25 kD) (4).
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