深圳欣博盛生物科技有限公司 a1

Dystrophin antibody [Dy4/6D3]
货号:GTX01871 规格:500μl 目录价:¥5000
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Dystrophin antibody [Dy4/6D3]
别名:
dystrophin , BMD , CMD3B , DXS142 , DXS164 , DXS206 , DXS230 , DXS239 , DXS268 , DXS269 , DXS270 , DXS272 , MRX85
反应种属:
Dog, Hamster, Human, Mouse, Pig, Rabbit, Rat
宿主来源:
Mouse
实验应用:
IHC-Fr
靶标/特异性:
This antibody reacts strongly with the rod domain (between amino acids 1181 and 1388) of human dystrophin. No reactivity with mdx mouse tissue of DMD/BMD patients who have a gene deletion which removes the antibody binding site.,We do not recommend use of this product for Chicken.
同种型:
IgG2a
免疫原:
Bacterial fusion protein (Hoffman EP et al., 1987).
克隆性:
Monoclonal
克隆号:
Dy4/6D3
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
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