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折扣/货期| 货号：GTX640841 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX640841-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E-Cadherin (phospho Ser838/Ser840) antibody [HL3201]
别名:
cadherin 1 , Arc-1 , BCDS1 , CD324 , CDHE , ECAD , LCAM , UVO
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody detects E-Cadherin when dually phosphorylated at Ser838 and Ser840, but it does not recognize E-Cadherin when singly phosphorylated at either Ser838 or Ser840.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Ser838/Ser840 of human E-Cadherin. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3201
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
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