E2F1 antibody [16G7]-单抗-深圳欣博盛生物科技有限公司

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E2F1 antibody [16G7]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX70163

规格：100μl

目录价：￥4300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

E2F1 antibody [16G7]

别名:

E2F transcription factor 1 , E2F-1 , RBAP1 , RBBP3 , RBP3

反应种属:

Human, Mouse

宿主来源:

Mouse

实验应用:

ICC/IF, IP, WB

同种型:

IgG1

免疫原:

The region encoding the DNA binding domain (amino acids 244-264) of E2F-1 expressed in E. coli.

克隆性:

Monoclonal

克隆号:

16G7

纯化方式:

Affinity purified by Protein G.

偶联:

Unconjugated

产品浓度:

1.86 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]

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