官网链接
折扣/货期| 货号：GTX70154 | 规格：100μl | 目录价：￥4300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E2F1 antibody [17E2]
别名:
E2F transcription factor 1 , E2F-1 , RBAP1 , RBBP3 , RBP3
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
IHC-P, IP, WB
靶标/特异性:
This antibody recognizes E2F-1 that was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter.
同种型:
IgG1
免疫原:
The transactivation and retinoblastoma protein binding domain (amino acids 332-390) of E2F-1 expressed in E. coli.
克隆性:
Monoclonal
克隆号:
1700
纯化方式:
Protein G affinity purified.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
47
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
您可能感兴趣的产品
4-Hydroxy Nonenal [HNEJ-1] Monoclonal Antibody (Clone IG10) - Biotinylated
货号：45026
PD-1/CD279 Recombinant Monoclonal Antibody (Clone Pembrolizumab)
货号：45002
Sulfatide Recombinant Monoclonal Antibody (Clone GAMEG3)
货号：44723
Mertansine Monoclonal Antibody (Clone 2D12)
货号：44707
MMAE Monoclonal Antibody (Clone 1G1)
货号：44706
Microsomal Epoxide Hydrolase Monoclonal Antibody (Clone 1H9)
货号：44096
DNA/RNA Oxidative Damage Express ELISA Antibody
货号：401155
Cyclic CMP ELISA Monoclonal Antibody
货号：401106
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询