| 货号:GTX60615 | 规格:100μg | 目录价:¥5800 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
E2F1 antibody [8G9]
别名:
E2F transcription factor 1 , E2F-1 , RBAP1 , RBBP3 , RBP3
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ELISA, FCM, IHC-P, WB
同种型:
IgG1
免疫原:
Purified recombinant fragment of human E2F1 (AA: 69-223) expressed in E. Coli.
克隆性:
Monoclonal
克隆号:
8G9
纯化方式:
Protein G Purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
47
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
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